食品伙伴網(wǎng)訊  2019年11月7日，歐盟食品安全局發(fā)布關(guān)于來(lái)自?xún)煞N轉基因谷氨酸棒桿菌（Corynebacterium glutamicum）菌株的L-賴(lài)氨酸鹽酸鹽（L-Lysine Monohydrochloride）和L-賴(lài)氨酸濃縮液體（concentrated liquid l‐lysine）安全性和有效性的評估結果。

 

　　據了解，兩種產(chǎn)生L-賴(lài)氨酸鹽酸鹽（鹽酸，最低98.5%）和L-賴(lài)氨酸濃縮液體（堿，最低50%）的基因谷氨酸棒桿菌菌株為NRRL‐B‐67439 或 NRRL B‐67535，該添加劑旨在用于所有動(dòng)物物種的飼料或飲用水中。

 

　　部分原文報道如下：

 

　　The European Commission asked EFSA for an opinion on the safety for the target animals, consumer, user and the environment and on the efficacy of a l‐lysine monohydrochloride （HCl, minimum 98.5%） and of a concentrated liquid l‐lysine （base, minimum 50%） produced by genetically modified strains of Corynebacterium glutamicum （NRRL‐B‐67439 or NRRL B‐67535）。 They are intended to be used in feed or water for drinking for all animal species and categories. Neither viable cells of the production strains C. glutamicum strains NRRLB‐67439 or NRRL B‐67535; nor their recombinant DNA were detected in the final products. Therefore, those products do not pose any safety concern associated with the genetic modification of the production strains. l‐Lysine HCl and concentrated liquid l‐lysine （base） produced by C. glutamicum strains NRRLB‐67439 or NRRL B‐67535 are considered safe for the target species, for the consumer and for the environment. l‐Lysine HCl produced by C. glutamicum strains NRRL B‐67439 or NRRL B‐67535 is considered not irritant to skin or eyes and not a skin sensitiser. In the absence of data, the FEEDAP Panel cannot conclude on the potential toxicity by inhalation of l‐lysine HCl produced by C. glutamicum strains NRRL B‐67439 or NRRL B‐67535. Concentrated liquid l‐lysine （base） produced by C. glutamicum strains NRRL B‐67439 or NRRL B‐67535, due to its high pH （10.7 and 10.9, respectively） is anticipated to be corrosive to skin and eyes and poses a risk by inhalation. l‐Lysine HCl and concentrated liquid l‐lysine （base） produced by C. glutamicum strains NRRLB‐67439 or NRRL B‐67535 are considered as efficacious sources of the essential amino acid l‐lysine for non‐ruminant animal species. For the supplemental l‐lysine to be as efficacious in ruminants as in non‐ruminant species, it would require protection against degradation in the rumen.

 

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