食品伙伴網(wǎng)訊  2020年2月26日，據歐盟食品安全局（EFSA）消息，應歐盟委員會(huì )要求，歐盟動(dòng)物飼料添加劑和產(chǎn)品（FEEDAP）研究小組就Availa®Cr（DL‐蛋氨酸鉻螯合物（chromium chelate of DL‐methionine））作為奶牛飼料添加劑的安全性和有效性發(fā)表科學(xué)意見(jiàn)。

 

　　經(jīng)過(guò)評估，專(zhuān)家小組認為在建議使用水平（奶牛每天8mg鉻來(lái)自Availa®Cr；大約0.4mg鉻/kg全價(jià)飼料）是安全的，但無(wú)法確定其有效性。部分原文報道如下：

 

　　Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Availa®Cr （active compound: chromium chelate of DL‐methionine） as a feed additive for dairy cows. The EFSA Panel on Additives and Products or Substances used in Animal Feed （FEEDAP） Panel was assigned to this mandate. The tolerance study did not show adverse effects with respect to body weight, milk yield, haematology and blood biochemistry up to the 10‐fold overdose of chromium from Availa®Cr; however, owing to deficiencies in design and reporting of the study, it provided only supportive evidence on the safety of the additive. A safe level for dairy cows could be derived from a toxicological study with laboratory rodents. Taking all together, the FEEDAP Panel considers the maximum recommended use level （8 mg Cr from Availa®Cr/cow per day; about 0.4 mg Cr/kg complete feed） as safe. Chromium DL‐Met shows a genotoxic activity in vitro that is not expressed in vivo after systemic exposure; although no data on genotoxicity at the site of contact are available, the Panel notes that chromium（III） is not carcinogenic and concludes that chromium DL‐Met is unlikely to pose a carcinogenic risk at levels occurring in the diet.

 

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